Principle Of E-Nose
Mimicking the nose is a
challenging task. The human nose can smell 10,000 different odour molecules
mixed in air. Odour in a substance is due to certain volatile organic compounds
(VOCs), which easily evaporate and get carried by an air stream. An e-nose can
smell and estimate odours quickly though it has little or no resemblance to the
human nose. A human nose has receptors, which serve as binding sites for VOCs.
A receptor is just a molecular structure on the surface of the nerve cell to
which an odorous molecule with the right shape binds. The receptor and the
binding molecule fit exactly as in a key and lock arrangement. These
odour-sensing nerve cells line the upper part of the cavity in the human nose. Once
an odour molecule binds to a receptor, a chain reaction follows which
ultimately transmits an electrical signal to the brain. A specific odour of
coffee or wine is usually caused not by one, but a mixture of hundreds of
organic compounds. So, the brain has a mammoth task of processing signals
received from the nerve cells originating from the nose, to identify the nature
of smell. The exact working of the brain in processing these signals is yet to
be fully understood.
Abstract
In an ever-developing world, where electronic devices are
duplicating every other sense of perception, the sense of smell is lagging
behind. Yet, recently, there has been an urgent increase in the need for
detecting odours, to replace the human job of sensing and quantification.
Nose on a Chip
When he arrives home
from vacation, Clarence’s smart alarm system deluges him with messages. Natural
gas is leaking from the furnace. Smoke is present in a guest bedroom. Food is
spoiling in the refrigerator. In the garage, a paint can lid apparently has
come loose, and a container of insecticide is leaking. Such a warning
capability may be possible someday, thanks to ORNL’s invention of a “nose on a chip.”
This wireless electronic nose can simultaneously detect and measure a variety
of vapors in the air and signal a receiver to sound an alarm or display a
message. Already tests of this first battery-operated cantilever array sensor
chip set have shown it can simultaneously sense various combinations of
hydrogen, nitric oxide, mercury vapor, and alkane thiols in the air. Because
the device is inexpensive and can provide instant results, it could soon be
incorporated into household gas appliances to warn of hazardous leaks.
Introduction
In the past decade, electronic nose
instrumentation has generated much interest internationally for its potential
to solve a wide variety of problems in fragrance and cosmetics production, food
and beverages manufacturing, chemical engineering, environmental monitoring,
and more recently, medical diagnostics and bioprocesses. Several dozen
companies are now designing and selling electronic nose units globally for a
wide variety of expanding markets. An electronic nose is a machine that is
designed to detect and discriminate among complex odours using a sensor array.
The sensor array of consists of broadly tuned (non-specific) sensors that are
treated with a variety of odour-sensitive biological or chemical materials. An
odour stimulus generates a characteristic fingerprint (or smell-print) from the
sensor array. Patterns or fingerprints from known odours are used to construct
a database and train a pattern recognition system so that unknown odours can
subsequently be classified and identified. Thus,electronic nose instruments
are comprised of hardware components to collect and transport odours to the
sensor array – as well as electronic circuitry to digitise and stored the
sensor responses for signal processing.
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